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Next Generation Sequencing: an Emerging Bioinformatics Field

A. Jiwan1 , S. Singh2

  1. Dept. of Computer Science and Engineering, Punjab Engineering College (Deemed to be University), Chandigarh, India.
  2. Dept. of Computer Science and Engineering, Punjab Engineering College (Deemed to be University), Chandigarh, India.

Correspondence should be addressed to: ankita9506@gmail.com.

Section:Research Paper, Product Type: Journal Paper
Volume-5 , Issue-12 , Page no. 130-134, Dec-2017

CrossRef-DOI:   https://doi.org/10.26438/ijcse/v5i12.130134

Online published on Dec 31, 2017

Copyright © A. Jiwan, S. Singh . This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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IEEE Style Citation: A. Jiwan, S. Singh, “Next Generation Sequencing: an Emerging Bioinformatics Field,” International Journal of Computer Sciences and Engineering, Vol.5, Issue.12, pp.130-134, 2017.

MLA Style Citation: A. Jiwan, S. Singh "Next Generation Sequencing: an Emerging Bioinformatics Field." International Journal of Computer Sciences and Engineering 5.12 (2017): 130-134.

APA Style Citation: A. Jiwan, S. Singh, (2017). Next Generation Sequencing: an Emerging Bioinformatics Field. International Journal of Computer Sciences and Engineering, 5(12), 130-134.

BibTex Style Citation:
@article{Jiwan_2017,
author = {A. Jiwan, S. Singh},
title = {Next Generation Sequencing: an Emerging Bioinformatics Field},
journal = {International Journal of Computer Sciences and Engineering},
issue_date = {12 2017},
volume = {5},
Issue = {12},
month = {12},
year = {2017},
issn = {2347-2693},
pages = {130-134},
url = {https://www.ijcseonline.org/full_paper_view.php?paper_id=1591},
doi = {https://doi.org/10.26438/ijcse/v5i12.130134}
publisher = {IJCSE, Indore, INDIA},
}

RIS Style Citation:
TY - JOUR
DO = {https://doi.org/10.26438/ijcse/v5i12.130134}
UR - https://www.ijcseonline.org/full_paper_view.php?paper_id=1591
TI - Next Generation Sequencing: an Emerging Bioinformatics Field
T2 - International Journal of Computer Sciences and Engineering
AU - A. Jiwan, S. Singh
PY - 2017
DA - 2017/12/31
PB - IJCSE, Indore, INDIA
SP - 130-134
IS - 12
VL - 5
SN - 2347-2693
ER -

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Abstract

DNA sequences are the store house of all the biological information. DNA sequencing focuses on determining the exact order of the nucleotides in a DNA sequence. Many research efforts have been put to the development of cheaper and increasingly higher-throughput sequencing techniques. This lead to development of a massively parallel and efficient method called as Next Generation Sequencing (NGS). The massively parallel NGS technologies have a high throughput with reduced cost. This paper gives a brief working principle of sequencer such as Roche 454 (GS FLX Titanium/GS Junior), Illumina (Genome Analyzer/HiSeq 2000/MiSeq) and Life Technologies (SOLiD/Ion Torrent PGM) along with a their comparison.

Key-Words / Index Term

Next generation sequencing, Roche, Illumina, SOLiD, Sanger

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